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目的对比不同术式对宫颈上皮内瘤变Ⅲ级患者预后质量的影响差异。方法回顾性分析104例宫颈上皮内瘤变Ⅲ级患者的临床资料,根据术式将其分成研究组(A组,n=54)和对照组(B组,n=50)。A组采用宫颈冷刀锥切术,B组采用子宫全切术。比对两组患者术程、术中失血量、总住院时间、术后肠道功能恢复时间等治疗指标差异,记录其术后并发症发生情况、复发率及性生活满意度差异。结果 1A组术程、术中失血量、总住院时间、术后肠道功能恢复时间等治疗指标均显著低于B组(P<0.05);2A组术后并发症发生率为3.8%,复发率为3.8%,与B组的7.4%和4.0%比较,差异未见统计学意义(P>0.05);B组术后性生活满意度为62.0%,显著低于A组的88.9%(P<0.05)。结论对宫颈上皮内瘤变Ⅲ级患者予以宫颈冷刀锥切术,术程短、术后恢复期短且并发症发生率低,可有效提高患者术后性生活满意度,值得临床推广。
Objective To compare the differences of prognosis of patients with grade Ⅲ cervical intraepithelial neoplasia by different surgical procedures. Methods The clinical data of 104 patients with grade Ⅲ cervical intraepithelial neoplasia were retrospectively analyzed. They were divided into study group (group A, n = 54) and control group (group B, n = 50) according to the surgical procedures. A group of cervical cold knife conization, B group using hysterectomy. The differences between the two groups in the duration of operation, intraoperative blood loss, total length of hospital stay, and postoperative recovery time of intestinal function were compared. The incidence of postoperative complications, recurrence rate and sexual satisfaction were recorded. Results The therapeutic indexes of operation duration, intraoperative blood loss, total length of stay, postoperative intestinal function recovery time in group A were significantly lower than those in group B (P <0.05). The incidence of postoperative complications in group A was 3.8% The difference was not statistically significant (P> 0.05). The postoperative sexual satisfaction in group B was 62.0%, which was significantly lower than that in group A (88.9%, P <0.05). Conclusion Cervical intraepithelial neoplasia grade Ⅲ patients with cervical cold knife conization, short course, short recovery period and the incidence of complications is low, which can effectively improve the postoperative sexual satisfaction of patients, it is worth clinical promotion.