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目的了解本地妊娠期妇女TORCH[刚地弓形虫(TOX)、风疹病毒(RV)、巨细胞病毒(CMV)和单纯性疱疹病毒(HSV)]感染检出情况和妊娠结局,为加强孕妇保健、促进优生优育工作提供参考依据。方法选择青田县妇幼保健所2013年1月至2014年12月产科接收的365例孕妇为研究对象,回顾性分析其血清标本中TORCH(TOX、RV、CMV和HSV)的特异性IgM、IgG检测结果,并总结妊娠结局。结果妊娠期妇女TOX、RV、CMV和HSV-IgM阳性率分别为0.82%、1.34%、3.01%和4.38%;IgG阳性率分别为2.74%、57.26%、85.48%和81.64%。TORCH-IgM阳性孕妇出现不良妊娠结局的概率为31.43%,显著高于TORCH-IgM阴性孕妇的1.81%(P<0.01)。结论妊娠期妇女TORCH感染是不良妊娠结局的重要危险因素,应加强临床宣传工作和产前筛查,达到优生优育的目的。
Objective To understand the detection of TORCH (TOX, RV, CMV and HSV) infection and pregnancy outcome among pregnant women in the first trimester of pregnancy. To enhance the health care of pregnant women, Promote eugenics and maternity provide reference. Methods A total of 365 pregnant women who received obstetrics from January 2013 to December 2014 in Qingtian MCH were selected as study objects. The results of specific IgM and IgG test of TORCH (TOX, RV, CMV and HSV) in serum samples were retrospectively analyzed , And summarize the pregnancy outcome. Results The positive rates of TOX, RV, CMV and HSV-IgM in pregnant women were 0.82%, 1.34%, 3.01% and 4.38% respectively. The positive rates of IgG were 2.74%, 57.26%, 85.48% and 81.64% respectively. The probability of adverse pregnancy outcomes in TORCH-IgM positive pregnant women was 31.43%, significantly higher than that in TORCH-IgM negative pregnant women (1.81%, P <0.01). Conclusion TORCH infection in pregnant women is an important risk factor for adverse pregnancy outcomes. Clinical advocacy work and prenatal screening should be strengthened to achieve prenatal and postnatal care.