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为了探讨低分子肝素(LMWH)在脑梗塞应用中的安全性及实用性,采用随机单盲对照方法,对39例急性脑梗塞病人,予LMWH治疗,并与低分子右旋糖酐治疗进行比较。结果显示:LMWH组对不同程度患者的神经功能恢复程度明显优于低右组(P<001),LMWH组头颅CT扫描脑梗塞体积缩小的范围比对照组明显(P<005),LMWH不减少血小板数量及纤维蛋白量,不引起出血,可改善血液流变学,降低微循环总积分值。总有效率8718%。
In order to investigate the safety and practicability of low molecular weight heparin (LMWH) in the treatment of cerebral infarction, 39 patients with acute cerebral infarction were treated with LMWH and compared with low molecular weight dextran treated with a single randomized controlled trial. The results showed that the degree of neurological recovery in LMWH group was significantly better than that in the low right group (P <001), and the extent of cerebral infarction volume reduction in the LMWH group was more obvious than that in the control group (P <005) , LMWH does not reduce the number of platelets and fibrin amount, does not cause bleeding, can improve blood rheology, reduce the total microcirculation value. The total effective rate 87.18%.