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目的探讨干预治疗对妊娠期糖尿病患者的胎儿和婴儿的心脏功能的影响。方法将符合诊断的99例患者随机分成干预治疗组和对照组,两组患者均给予饮食控制血糖水平,干预治疗组在对照组的基础上再给予胰岛素控制血糖水平。通过超声心动图观察胎儿及婴儿的心脏功能。结果比较两组胎儿超声可以看出,干预治疗组胎儿胎心记录室间隔缺损、动脉导管未闭、心肌肥厚、房间隔缺损的发生率分别为12.07%、13.79%、10.34%、8.62%均少于对照组的各项发生率46.34%、31.71%、26.83%、31.71%,P﹤0.05。干预治疗组室间隔缺损、动脉导管未闭合、肺动脉高压、心肌肥厚的发生率分别为8.62%、12.07%、3.45%、6.9%,低于对照组24.39%、31.71%、19.51%、26.83%,P﹤0.05。结论干预治疗能够有效地减少妊娠期糖尿病胎儿和婴儿的心脏功能异常。
Objective To investigate the effect of intervention on cardiac function in fetus and infants with gestational diabetes mellitus. Methods Ninety-nine patients who were diagnosed were randomly divided into intervention group and control group. The two groups were given diet-controlled blood glucose levels. The intervention group was given insulin-controlled blood glucose level on the basis of the control group. Fetal and infant heart function observed by echocardiography. Results Comparing the two groups of fetal ultrasound, we can see that the incidences of fetal heart rate ventricular septal defect, patent ductus arteriosus, cardiac hypertrophy and atrial septal defect in intervention group were 12.07%, 13.79%, 10.34% and 8.62% respectively The incidence of the control group of 46.34%, 31.71%, 26.83%, 31.71%, P <0.05. The incidence of ventricular septal defect, patent ductus arteriosus, pulmonary hypertension and cardiac hypertrophy in intervention group were 8.62%, 12.07%, 3.45% and 6.9%, respectively, which were lower than that in control group by 24.39%, 31.71%, 19.51% and 26.83% P <0.05. Conclusion Intervention treatment can effectively reduce cardiac dysfunction in gestational diabetic fetus and infants.