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呼肠病毒致病各阶段的发病机理呼肠病毒是通过胃肠道进入宿主。在最初潜伏期内,呼肠病毒1型在淋巴样组织中增殖,4～6天内扩散至更远的器官,且病毒浓度升高,感染后产生体液和细胞免疫。病毒接种后约1周,血清中可检出中和与血凝抑制抗体。型特异细胞毒T细胞、迟发型超敏反应和抑制性T细胞先于抗体反应。呼肠病毒在宿主细胞中通常产生溶细胞性感染,但在体外也可引起持续性感染。
Reovirus pathogenic pathogenesis at each stage reovirus enter the host through the gastrointestinal tract. During the initial incubation period, reovirus type 1 proliferates in lymphoid tissues, diffuses to farther organs within 4 to 6 days, and the virus concentration is elevated, producing humoral and cellular immunity after infection. About 1 week after virus inoculation neutralization and hemagglutination inhibition antibodies can be detected in the serum. Type specific cytotoxic T cells, delayed type hypersensitivity and suppressor T cells prior to antibody responses. Reovirus typically produces cytolytic infections in host cells but can also cause persistent infections in vitro.