论文部分内容阅读
目的分析肥胖伴高脂血症患者血清维生素D水平的变化,探讨维生素D水平与血脂及肥胖的关系。方法将91例门诊体检者分为肥胖伴高脂血症组(A组)27例、超体质量组(B组)33例、正常对照组(C组)31例,比较3组身高、体质量、血压等参数和血糖、血脂、甲状旁腺激素及1,25-二羟基维生素D3水平。结果 3组性别、年龄等比较差异无统计学意义(P>0.05),A,B,C组血清1,25-二羟基维生素D3分别为(21.65±4.97),(27.65±5.68),(33.58±8.54)ng/mL,A组与B,C组比较差异有统计学意义(P<0.05);1,25-二羟基维生素D3与腰围、体质量指数、收缩压、总胆固醇、三酰甘油、低密度脂蛋白胆固醇呈负相关。结论肥胖伴高脂血症患者血清维生素D水平降低,维生素D与肥胖及血脂关系密切。
Objective To analyze the changes of serum vitamin D levels in obese patients with hyperlipidemia and to explore the relationship between vitamin D levels and blood fat and obesity. Methods Totally 91 outpatients were divided into two groups: 27 with obesity and hyperlipidemia (group A), 33 with super body mass (group B) and 31 with normal control (group C) Quality, blood pressure and other parameters and blood glucose, blood lipids, parathyroid hormone and 1,25-dihydroxy vitamin D3 levels. Results There were no significant differences in sex, age and other three groups (P> 0.05). The serum 1,25-dihydroxyvitamin D3 in group A, B and C were (21.65 ± 4.97), (27.65 ± 5.68) and ± 8.54) ng / mL, the difference between group A and group B and C was statistically significant (P <0.05); The correlation between 1,25-dihydroxyvitamin D3 and waist circumference, body mass index, systolic blood pressure, total cholesterol, triglyceride , Low-density lipoprotein cholesterol was negatively correlated. Conclusions Serum vitamin D levels are decreased in obese patients with hyperlipidemia and vitamin D is closely related to obesity and blood lipids.