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目的 探讨在应用肾上腺皮质激素的基础上加用沐舒坦预防早产儿肺透明膜病 (HMD)的效果。方法 设激素 +沐舒坦组 (n =2 8)为观察组 ,单用激素为对照组 (n =35 ) ,观察两组早产儿HMD的发生率 ;观察两组窒息儿中HMD的发生情况及不同胎龄时HMD的发生率。结果 (1)对照组HMD的发生率为 11.4% ,观察组为 0 % ,两组有显著性差异 (P <0 .0 5 ) ;(2 )对照组中孕周 <32周、33～ 34周及 35～ 36周的早产儿HMD的发生率分别是 2 8.7%、15 .38%和 0 % ,而在观察组中均未发生 ;(3)对照激素组 12例窒息儿中有 3人发生HMD ,观察组 6例窒息儿中无一人发生HMD。结论 在产前应用激素的基础上 ,产后立即加用沐舒坦对预防早产儿HMD有一定的疗效
Objective To investigate the effect of using mucosolvan on the prevention of hyaline membrane disease (HMD) in preterm infants based on the application of adrenal cortical hormone. Methods Hormone + mucosolvan group (n = 28) was used as observation group and hormone alone was used as control group (n = 35). The incidence of HMD in both groups was observed. The incidence of HMD at different gestational ages. Results (1) The incidence of HMD was 11.4% in the control group and 0% in the observation group, with significant difference between the two groups (P <0.05). (2) The gestational weeks <32 weeks and 33-34 The incidence of HMD in preterm infants with weeks and 35-36 weeks were respectively 2. 8.7%, 15.38% and 0%, but not in the observation group. (3) There were 3 of 12 asphyxia children in the control hormone group HMD occurred and none of 6 asphyxiated children in the observation group developed HMD. Conclusion On the basis of prenatal hormone application, the immediate effect of using mucosolvan on the prevention of preterm infant HMD has a certain effect