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为阐明麻黄附子细辛汤(TJ-127)的抗变态反应作用,探讨了对化学介质、细胞因子及免疫球蛋白的影响。以ICR系雄性小鼠为对象,经口给予TJ-127,观察对组胺及佛波酯诱发水肿的影响。以BALB/c雄性小鼠,观察其对脾细胞生成的细胞因子IL-4和IFN=γ,抗体产生细胞生成的免疫球蛋白(IgE)的影响。结果:TJ-127对组胺诱发的水肿呈剂
In order to elucidate the antiallergic effects of Mahuang Fuzi Xixin Decoction (TJ-127), the effects of chemical mediators, cytokines and immunoglobulins were explored. The ICR male mice were orally administered with TJ-127 to observe the effects of histamine and phorbol ester induced edema. BALB/c male mice were observed for their effect on IL-4 and IFN=γ produced by spleen cells and immunoglobulin (IgE) produced by antibody-producing cells. Results: TJ-127 is active on histamine-induced edema