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迄今有许多涉及慢性粒细胞白血病(CML)的分类和预后的骨髓细胞学研究,然结果不够确切,甚至相互矛盾。为探讨临床和组织学特点对判断初诊CML预后的价值,我们观察了1975年1月～1989年10月数家医院初诊的130例CML。均为ph~1阳性、稳定期、周围血原始加早幼粒细胞少于20％。对患者骨髓活检组织进行糖原(PAS)和嗜银等组化染色和免疫组化染色,后者用单抗CD_(61)(Y2/51)确定巨核细胞成分,单抗PG—M1确定巨噬细胞,并同
To date, there have been many myelocytological studies involving the classification and prognosis of chronic myeloid leukemia (CML), but the results are not exact enough or even conflicting. In order to explore the clinical and histological characteristics of the prognosis of newly diagnosed CML, we observed 130 CML cases newly diagnosed in several hospitals from January 1975 to October 1989. Ph ~ 1 were positive, stable, peripheral blood primordial plus promyelocytic less than 20%. The bone marrow biopsy specimens of patients were histopathologically stained for glycogen (PAS) and argyrophil and immunohistochemical staining. The latter was identified by the monoclonal antibody CD 61 (Y2 / 51), and the monoclonal antibody PG-M1 Phagocytes, and the same