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纤维连结蛋白是一种存在于血浆和细胞表面的高分子糖蛋白,分子量约45万道尔顿。人体内纤维连结蛋白的含量,在100～400μg/ml之间。研究表明,纤维连结蛋白有助于角膜损伤的修复,并能影响小梁网的代谢和玻璃体、视网膜内界膜间的粘着。纤维连绪蛋白的生物胶作用已初步用于临床,对治疗角膜缺损收到了满意的效果。本文综述有关纤维连结蛋白的研究成果,并介绍纤维连结蛋白的提取方法。
Fibronectin is a high-molecular glycoprotein found in plasma and cell surfaces with a molecular weight of about 450,000 daltons. The amount of fibronectin in the human body is between 100 and 400 μg / ml. Studies have shown that fibronectin helps corneal injury repair, and can affect the metabolism of the trabecular meshwork and the adhesion between the vitreous body and the inner membrane of the retina. Fibroxilin protein has been initially applied to the clinical role of the glue, the treatment of corneal defects received satisfactory results. This article reviews research findings on fibronectin and describes the extraction of fibronectin.