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目的探讨软组织肿瘤术后放疗或化疗综合治疗的疗效,为临床治疗提供依据。方法 98例软组织肿瘤患者为研究对象,按照良、恶性肿瘤与病理类型采用相应的治疗方案进行治疗,分析不同病理类型及不同治疗方式患者的3年与5年生存率。结果随访5年发现,不同病理类型其3年和5年生存率存在差异,其中隆突性纤维肉瘤、脂肪肉瘤与平滑肌肉瘤的3年和5年生存率均为100.00%,而滑膜肉瘤和神经纤维肉瘤的5年生存率为0。不同病理类型总的3年生存率为59.18%,总的5年生存率为47.96%。不同治疗方式的3年与5年生存率也存在差异,其中采用手术+放疗+化疗治疗的3年与5年生存率最高,分别为63.64%和51.52%,手术+化疗的3年生存率最低,为41.18%;单纯手术的5年生存率最低,为18.18%。结论不同病理类型和治疗方式会对软组织肿瘤的治疗效果产生直接影响,而综合采用手术+放疗+化疗治疗对软组织肿瘤具有较好疗效,具有临床推广价值。
Objective To investigate the curative effect of radiotherapy or chemotherapy after soft tissue tumor surgery and provide basis for clinical treatment. Methods A total of 98 patients with soft tissue tumors were enrolled in this study. Patients were treated according to benign and malignant tumors and pathological types with corresponding treatment plans. The 3-year and 5-year survival rates of patients with different pathological types and different treatment methods were analyzed. Results The follow-up of 5 years showed that there were differences in the 3-year and 5-year survival rates of different pathological types. Among them, 3-year and 5-year survival rate of salivary fibrosarcoma, liposarcoma and leiomyosarcoma were 100.00%, while synovial sarcoma and The 5-year survival rate of neurofibrosarcoma is zero. The overall 3-year survival rate of different pathological types was 59.18%, and the overall 5-year survival rate was 47.96%. The 3-year and 5-year survival rates of different treatment methods were also different. The 3-year and 5-year survival rate of the patients treated with operation + radiotherapy + chemotherapy was the highest, 63.64% and 51.52% respectively, and the lowest 3-year survival rate of surgery + chemotherapy , 41.18%. The lowest 5-year survival rate was 18.18%. Conclusion Different pathological types and treatment methods will have a direct impact on the treatment of soft tissue tumors, and combined with surgery + radiotherapy + chemotherapy treatment of soft tissue tumors have a good effect, with clinical value.