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目的分析老年肺癌合并院内肺部真菌感染的危险因素,寻求防治措施。方法对洛阳市第一人民医院呼吸科2003-10-2009-10收治的26例老年肺癌并院内肺部真菌感染的病例进行临床分析。结果 26例中合并白色念珠菌感染18例,热带念珠菌感染2例,光滑念珠菌感染4例,酵母样菌1例,热带假丝酵母菌1例。其中8例应用氟康唑,2例应用伊曲康唑。住院期间10例病情好转,16例死亡。结论老年肺癌合并院内肺部真菌感染发病率高,预后差,易被忽视,值得临床工作者关注。
Objective To analyze the risk factors of pulmonary fungal infection in elderly patients with lung cancer and to seek prevention and treatment measures. Methods The clinical data of 26 elderly patients with lung cancer admitted to Department of Respiratory Diseases, First People’s Hospital of Luoyang, 2003-10-2009-10 were retrospectively analyzed. Results Of the 26 cases, 18 were infected with Candida albicans, 2 were infected with Candida tropicalis, 4 were Candida glabrata infection, 1 was yeast-like bacteria and 1 was Candida tropicalis. Among them, fluconazole was used in 8 cases and itraconazole was used in 2 cases. During the hospitalization, 10 patients got better and 16 died. Conclusion The incidence of pulmonary fungal infection in elderly patients with lung cancer is high, the prognosis is poor, easily overlooked, which deserves the attention of clinicians.