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目的评价代谢综合征与良性前列腺增生症之间的相关性。方法选取203例良性前列腺增生症患者根据有无代谢综合征分为两组进行前瞻性研究。代谢综合征的诊断依据最新的全美胆固醇教育计划成人治疗组Ⅲ指南发布的报告。测量血压、体重、身高、腰围和臀围,计算体重指数和腰臀比。生化检查包括血糖、总胆固醇、甘油三酯、高密度脂蛋白、胰岛素和前列腺特异性抗原。通过前列腺彩超测量前列腺体积。结果伴有代谢综合征的前列腺增生患者体重、体重指数、血糖、血清甘油三酯和前列腺特异性抗原的中位数均较对照组明显升高,前列腺体积明显大于对照组。结论现有研究表明代谢综合征可能促进前列腺的增生。
Objective To evaluate the correlation between metabolic syndrome and benign prostatic hyperplasia (BPH). Methods Totally 203 patients with benign prostatic hyperplasia were divided into two groups according to the presence or absence of metabolic syndrome and prospectively studied. The diagnosis of metabolic syndrome is based on the report released by the latest National Cholesterol Education Program Adult Treatment Group III guidelines. Blood pressure, weight, height, waist circumference and hip circumference were measured and body mass index and waist-to-hip ratio were calculated. Biochemical tests include blood glucose, total cholesterol, triglycerides, HDL, insulin, and prostate-specific antigens. Prostate volume was measured by ultrasound. Results The body mass, body mass index, blood glucose, serum triglyceride and median prostate-specific antigen in patients with BPH were significantly higher than those in the control group, and the volume of prostate was significantly larger than that in the control group. Conclusion Existing research shows that metabolic syndrome may promote prostate hyperplasia.