目的:探讨影响冠心病并肾动脉狭窄患者肾动脉支架术后血压改善的因素。方法:选取88例随访资料完整并术前并发高血压的冠心病患者。根据随访结果,将达到美国心脏协会(AHA)指南的肾动脉支架术后随访血压改善标准的53例作为血压改善组,其余35例血压无改善的为未改善组。比较2组临床特征和支架术后随访结果,并作多因素回归分析。结果:两组均成功行肾动脉支架置入术,入选患者术后总体血压改善率为60.2%。与血压改善组比较,血压未改善组患者年龄较高[(74.7±7.0)∶(69.6±7.8)岁,P<0.05],女性较多(62.9%∶35.9%,P<0.05),肾小球滤过率较低[(41.7±20.5)∶(50.4±20.3)ml/min,P<0.05]。多因素分析显示,年龄和性别是影响肾动脉狭窄患者支架术后血压改善的预测因素。结论:60%的冠心病并肾动脉狭窄患者肾动脉支架术后血压能得到改善,但高龄和女性患者术后血压获益较少。 Objective: To explore the factors influencing the improvement of blood pressure after renal artery stenting in patients with coronary artery disease and renal artery stenosis. Methods: Eighty-eight patients with coronary heart disease who had complete follow-up and preoperative hypertension were enrolled. According to the follow-up results, 53 patients who achieved the criteria of blood pressure improvement after renal artery stenting who reached the guidelines of the American Heart Association (AHA) as the blood pressure improvement group and 35 patients whose blood pressure did not improve as the uncorrected group. The clinical features and follow-up results of the two groups were compared and analyzed by multivariate regression analysis. Results: Renal artery stenting was successfully performed in both groups. The improvement rate of total blood pressure after the operation was 60.2%. Compared with the blood pressure improvement group, the patients with no improvement of blood pressure were older (74.7 ± 7.0), (69.6 ± 7.8) years old, P <0.05], more women (62.9%, 35.9%, P <0.05) The ball filtration rate was lower [(41.7 ± 20.5): (50.4 ± 20.3) ml / min, P <0.05]. Multivariate analysis showed that age and gender were predictors of improvement of blood pressure after stenting in patients with renal artery stenosis. CONCLUSIONS: Sixty percent of patients with coronary artery disease and renal artery stenosis have improved blood pressure after renal artery stenting, but the benefit of postoperative BP is lower in elderly and females.