原发于淋巴结外的非何杰金氏淋巴瘤(简称 NHL)常见于鼻咽部、胃肠及皮肤,容易诊断。而少见部位发病者则易被临床医生忽视。我院病理活检586例 NHL 中,发现原发于阑尾、乳腺、上颌骨及脾脏各1例,在病理检查前临床上均未考虑到淋巴瘤的可能性,本文就其临床表现、长期随访的结果及其误诊的原因报告如下。 Non-Hodgkin’s lymphoma (NHL), which is primary in the lymph nodes, is common in the nasopharynx, gastrointestinal tract and skin and is easy to diagnose. The incidence of rare parts are easily overlooked by clinicians. Pathological biopsy in our hospital 586 cases of NHL, found in the appendectomy, breast, maxillary and spleen in 1 case, before the pathological examination did not take into account the possibility of lymphoma, this article on its clinical manifestations, long-term follow-up The results and the reasons for the misdiagnosis are reported as follows.