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肝纤维化是慢性肝脏疾病进展为晚期肝功能衰竭过程中一个重要的阶段。关于肝纤维化机制及对其防治的研究,近年来已经成为国内外医学研究的热点之一,其中内毒素在肝纤维化中的作用越来越受到关注。本文综述了近些年国内外学者对内毒素与肝纤维化的研究,并对其机制进行探讨。
Liver fibrosis is an important stage in the progression of chronic liver disease to advanced liver failure. Research on the mechanism of liver fibrosis and its prevention and treatment has become one of the hot spots in medical research at home and abroad in recent years. The role of endotoxin in liver fibrosis has drawn more and more attention. This review summarizes the recent researches on endotoxin and hepatic fibrosis in China and abroad and explores its mechanism.