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The crystal-growing conditions and the results of preliminary X-ray crystallographic analysis of (L-Try)~(A1)-insulin and (D-Try)~(A1)-insulin are reported. The single crystals of this pair of insulin analogue suitable for X-ray diffraction analysis have been grown in the citrate buffer system by still-setting method. They both belong to the trigonal system with space group R3. The parameters of the unit cell (L-Trp)~(A1)-insulin are αH= 80.31, cH= 37.45 and those of (D-Trp)~(A1)-insulin αH = 79.48, cH = 43.81. There are two molecules in an asymmetric unit. The obtained results are discussed.
The crystal-growing conditions and the results of preliminary X-ray crystallographic analysis of (L-Try) ~ (A1) -insulin and (D-Try) ~ (A1) -insulin are reported. The single crystals of this pair of insulin analogue suitable for X-ray diffraction analysis have been grown in the citrate buffer system by still-setting method. They both belong to the trigonal system with space group R3. The parameters of the unit cell (L-Trp) ~ (A1) - insulin are αH = 80.31, cH = 37.45 and those of (D-Trp) ~ (A1) -insulin αH = 79.48, cH = 43.81. There are two molecules in an asymmetric unit.