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本研究观察了42例脑血管意外后遗症的老年患者和40例无明显心、脑血管疾病的老年人血红细胞SOD活性。结果发现,脑血管意外后遗症患者的红细胞SOD活性明显低于无心、脑血管疾病表现的老年人,其SOD活性分别为1268士54μ/gHb和1704士60μ/gHb。差异具有显著性意义(p<0.01)。实验表明,脑血管疾病患者可伴有血SOD活性降低,从而提示脑血管疾病的发生可能与自由基有一定关系。
In this study, 42 elderly patients with cerebrovascular accidental sequelae and 40 elderly patients without obvious cardiovascular and cerebrovascular diseases were observed for SOD activity. The results showed that SOD activity of erythrocytes in patients with cerebrovascular accident sequelae was significantly lower than that of elderly without cardiovascular or cerebrovascular disease, and their SOD activities were 1268 ± 54μg / gHb and 1704 ± 60μg / gHb, respectively. The difference was significant (p <0.01). Experiments show that patients with cerebrovascular disease may be associated with decreased activity of blood SOD, suggesting that the occurrence of cerebrovascular disease may have a certain relationship with free radicals.