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目的:研究儿童药物不良反应情况,为儿童合理用药提供更加有力的依据。方法:对本院2010年1月到2011年12月治疗过的204例儿童病例的资料进行回顾性分析,对其临床用药不良反应情况进行总结。结果:回顾性调查显示,通过静脉注射占总给药途径的72.3%,在用药种类上,以抗菌类用药为主,占48.2%。儿童用药不良反应主要表现在皮肤上,占41.1%。结论:儿童用药所产生的不良反应主要是由于抗菌类药物及静脉注射引起的,因此,要提高儿童用药的安全性,关键是监管部门与医疗机构一起努力,规范儿童的用药类型及用药剂量,对于不必使用的抗生素,以少使用为佳。
Objective: To study the adverse drug reactions in children and provide a more powerful basis for rational drug use in children. Methods: The data of 204 cases of children treated in our hospital from January 2010 to December 2011 were retrospectively analyzed, and the clinical adverse reactions were summarized. Results: Retrospective survey showed that intravenous injection accounted for 72.3% of the total route of administration. In terms of the types of drugs, antibacterial drugs were predominant, accounting for 48.2%. Adverse drug reactions in children mainly in the skin, accounting for 41.1%. Conclusion: The adverse reactions of children’s medication are mainly caused by antibacterial drugs and intravenous injection. Therefore, to improve the safety of children’s medication, the key is that regulators and medical institutions work together to standardize the type of children’s medication and dosage, For non-use of antibiotics, less use is better.