目的　了解南昌地区亚临床甲状腺功能减退症 (SCH)的患病率。方法　于 1997年 12月～ 1998年 6月 ,对南昌地区的四县五区 2 110人 ,其中成人 14 4 2人 ,年龄为 (18～ 70岁 ) ;儿童 6 6 8人 ,年龄为 (3岁～ 6岁 11个月 ) ,进行甲状腺激素筛查测定。结果　 (1)南昌地区SCH总患病率 6 .1% ,其中成人患病率为 4 .6 % ,儿童患病率 9.1% ,儿童患病率高于成人 (P <0 .0 0 1) ;(2 )女性患病率为 7.4 % ;男性患病率为 4 .9% ,女性患病率高于男性 (P <0 .0 5 ) ;(3)SCH患病率与年龄结构比表明 :成人组 :6 0岁以上年龄组患病率最高 10 .4 % ,其次 5 0岁组 (5 .7% )和 18岁组 (5 .6 % ) ,但后两组比较差异无显著性 ,说明两个年龄段皆为患病高峰期。儿童组则以 3岁年龄组 ,患病率最高 (15 .9% ) ,其次是 6岁年龄组 (9.5 % ) ,两者自比或与成人组比较 ,差异皆有显著性 (P <0 .0 5 ) ;(4)SCH的患病率与甲状腺肿的发生无明显相关性。结论　南昌地区SCH的患病率较高 ,SCH的发生与性别和年龄相关 Objective To understand the prevalence of subclinical hypothyroidism (SCH) in Nanchang. Methods From December 1997 to June 1998, 2 1101 people in four counties and five districts of Nanchang were enrolled. Among them, 14,42 adults were aged 18 to 70 years old and 6,68 children aged 3 years Aged ~ 6 years and 11 months), thyroid hormone screening test. Results (1) The overall prevalence of SCH in Nanchang was 6.1%, of which, the prevalence rate was 4.66% in adults and 9.1% in children, and the prevalence rate in children was higher than that in adults (P0.01) ; (2) The prevalence rate of females was 7.4%; the prevalence of males was 4.9%, the prevalence of females was higher than that of males (P <0.05); (3) : Adult group: the highest prevalence was 10.4% in the group of over 60 years old, followed by the group of 50 years old (5. 7%) and the age group of 18 years old (5.6%), but the difference between the latter two groups was not significant , Indicating that both age groups are the peak of the disease. The prevalence of children in the 3-year-old group was the highest (15.9%), followed by the 6-year-old group (9.5%), both of which were significantly higher than those of the adult group .0 5); (4) There was no significant correlation between the prevalence of goiter and the incidence of goiter. Conclusion The prevalence of SCH in Nanchang is high, and the incidence of SCH is related to gender and age