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目的评价生长抑素、奥曲肽在肝硬化上消化道出血中的应用价值。方法研究选择我院收治的肝硬化上消化道出血患者80例,患者均于2015年1月-2016年10月入院治疗。随机性分组,对照组予以奥曲肽治疗,共40例;实验组予以生长抑素治疗,共40例。观察两组患者的治疗情况,并进行比较。结果在总有效率方面,实验组为97.5%(39/40),对照组为75%(30/40),实验组的总有效率比对照组高,组间数据差异性明显且统计学意义成立,P<0.05;在止血时间方面,实验组比对照组短,组间数据差异性明显且统计学意义成立,P<0.05;在输血量方面,实验组输血量比对照组少,组间数据差异性明显且统计学意义成立,P<0.05;在不良反应方面,两组患者差异性不明显,P>0.05。结论应用生长抑素对肝硬化上消化道出血患者进行治疗,能够改善患者病情,加快止血时间,安全性高,值得推荐。
Objective To evaluate the value of somatostatin and octreotide in the treatment of upper gastrointestinal hemorrhage due to cirrhosis. Methods 80 patients with cirrhosis and upper gastrointestinal bleeding admitted to our hospital were enrolled in this study. All patients were admitted to hospital from January 2015 to October 2016. Random group, the control group to be octreotide treatment, a total of 40 cases; the experimental group was treated with somatostatin, a total of 40 cases. The treatment of the two groups was observed and compared. Results The total effective rate was 97.5% (39/40) in the experimental group and 75% (30/40) in the control group. The total effective rate in the experimental group was higher than that in the control group, and the difference between the two groups was statistically significant (P <0.05). In terms of hemostasis time, the experimental group was shorter than the control group, the difference between the groups was significant and the statistical significance was established (P <0.05). In the transfusion volume, the transfusion volume of the experimental group was less than that of the control group, Significant difference between the data and statistical significance, P <0.05; adverse reactions, the two groups of patients with no significant difference, P> 0.05. Conclusions The use of somatostatin in patients with cirrhosis of upper gastrointestinal bleeding can improve the patient’s condition, accelerate the bleeding time, high safety, it is recommended.