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目的探讨不同孕周妊娠期糖尿病合并早发型重度子痫前期的临床特征及对母婴结局的临床影响。方法 56例妊娠期糖尿病合并早发型重度子痫前期产妇,根据孕周不同将其分为a组(32例,孕周<31周)与b组(24例,孕周31~33周)。两组产妇均给予相应治疗。观察比较两组产妇期待治疗时间、并发症、围生儿结局。结果 b组产妇期待治疗时间(7.81±2.54)d短于a组的(10.34±3.24)d、严重并发症总发生率29.17%低于a组的62.50%,差异均具有统计学意义(P<0.05)。b组新生儿窒息、胎儿生长受限、新生儿脑室内出血发生率4.17%、4.17%、8.33%均低于a组的25.00%、28.13%、31.25%,Apgar评分(8.32±1.62)分高于a组的(6.13±1.22)分,差异均具有统计学意义(P<0.05)。结论妊娠期糖尿病合并早发型重度子痫前期孕周越小对母婴危害越大,且母婴结局越差。
Objective To investigate the clinical features of different gestational weeks gestational diabetes mellitus combined with early-onset severe preeclampsia and its clinical impact on maternal and infant outcomes. Methods 56 pregnant women with gestational diabetes mellitus and early-onset severe preeclampsia were divided into group a (32 cases, gestational age <31 weeks) and group b (24 cases, gestational age 31-33 weeks) according to their gestational age. Two groups of maternal were given the appropriate treatment. Observe and compare expectant treatment time, complications and perinatal outcome in two groups. Results The expectant duration of treatment in group b was shorter than that in group a (7.84 ± 3.24) days, the total incidence of serious complications was 29.17%, lower than that in group a (62.50%, P < 0.05). In group b neonatal asphyxia and fetal growth restriction, the incidences of neonatal intraventricular hemorrhage were 4.17%, 4.17% and 8.33%, respectively, which were lower than those in group a 25.00%, 28.13% and 31.25%, Apgar score 8.32 ± 1.62 A group (6.13 ± 1.22) points, the difference was statistically significant (P <0.05). Conclusion The smaller the gestational age in gestational diabetes mellitus with early-onset severe preeclampsia is, the greater the harm to mothers and infants, and the worse the maternal and infant outcomes.