用酶联免疫吸附试验（ＥＬＩＳＡ）法测定４９例单眼视网膜脱离患者视网膜下液中ＩＬ－１β及ＴＮＦ－α含量。结果表明：所有视网膜下液中ＩＬ－１β含量增加且与ＰＶＲ病变严重程度呈线性正相关（ｒ＝０．６７７）；与年龄、性别、视网膜脱离范围、视网膜脱离时间、裂孔数目无明显相关。４９例视网膜下液中仅１８例含ＴＮＦ－α，其中ＰＶＲ－Ｃ１级以上病例占１６例（３２．６５％）。提示ＩＬ－１β和ＴＮＦ－α参与ＰＶＲ的形成和发展过程 The levels of IL-1β and TNF-α in subretinal fluid of 49 patients with monocular retinal detachment were detected by enzyme linked immunosorbent assay (ELISA). The results showed that the content of IL-1β in all subretinal fluid increased linearly with the severity of PVR (r = 0.677). There was no significant correlation between the level of IL-1β and age, sex, extent of retinal detachment, retinal detachment time and number of hiatus. Only 49 cases of subretinal fluid containing 18 cases of TNF-α, of which PVR-C1-level or more cases accounted for 16 cases (32.65%). It is suggested that IL-1β and TNF-α are involved in the process of PVR formation and development