癌症的原发病灶会将一些肿瘤细胞释放到血液中。这些细胞一般具有侵袭性,并对失巢凋亡具有耐受。因此,它们能在肿瘤原发部位之外的器官(如肝脏、骨骼、肺部和大脑)安家,产生新的肿瘤。尽管目前对这些细胞的研究还非常不足,研究人员们相信这些细胞可能是依赖于趋化因子的浓度梯度而发生的迁徙,或是依赖于这些细胞表面表达的特定受体。一些研究表明,如果这些细胞要脱离原发病灶或其他的转移性位点,它 The primary lesion of cancer releases some of the tumor cells into the bloodstream. These cells are generally aggressive and are resistant to anoikis. As a result, they can colonize organs outside the tumor’s primary site, such as the liver, bone, lung and brain, creating new tumors. Despite the current lack of research on these cells, the researchers believe that these cells may migrate depending on the concentration gradient of the chemokines or depend on specific receptors expressed on the surface of these cells. Some studies have shown that if these cells are to be detached from the primary lesion or other metastatic site, it