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1934年 Lundy 首先应用硫喷妥钠于临床,很快就得到推广。到60年代估计世界上每年应用 SP 作为全麻的诱导有数百万次之多。由于该药对呼吸和循环有明显的抑制,加之诱导过程中各种药物药量掌握,静脉推注的速度不一,全麻诱导时和其它药物的复合又多种多样,有时不免会发生轻重不等的意外,甚至造成死亡,遇到这些情况必然要作回顾性分析,从中吸取教训。切不可轻易地认为这是由于硫喷妥钠的过敏所致,忽视确切的诱因,本文复习有关硫喷妥钠过敏的文献,供临床实践中参考。
In 1934 Lundy first application of thiopental in clinical and soon to be promoted. By the 1960s it was estimated that millions of times more annual induction of SP as general anesthesia in the world. Because of the drug on the respiratory and circulatory inhibition was significantly inhibited, coupled with the induction of various drug dose control, intravenous injection at different speeds, induction of general anesthesia and other drugs and a variety of complex, sometimes inevitably occur weight Unending accidents and even deaths inevitably require a retrospective analysis in the face of these situations and draw lessons from them. Must not easily think that this is due to the allergy caused by thiopental, ignoring the exact cause, this review of the literature on thiopental allergy, for clinical practice reference.