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对湖北地区非职业铅接触的 90名孕妇和新生儿血铅及生长发育情况进行了追踪调查。结果显示 :孕 2 8周内血铅水平为 0 2 90 μmol/L ,分娩前为 0 32 6 μmol/L ,孕期血铅水平呈增高趋势。新生儿脐血血铅含量为 0 333μmol/L ,其中 17 8%的新生儿脐血血铅含量高于 0 483μmol/L。逐步回归分析显示新生儿脐血血铅含量 (Y3)与孕 2 8周内血铅 (Y1)及分娩前血铅 (Y2 )均有高度线性关系 :Y3 =0 12 2 5 10 6 7+0 16 0 945 91Y1+ 0 780 7786 5Y2。Y3与Y2之间的直线相关系数r=0 6 80 5 ,P <0 0 1。但母体铅暴露水平对胎儿生长发育尚未造成明显影响
A total of 90 pregnant women and newborns with non-occupational lead exposure in Hubei Province were investigated for blood lead and growth and development. The results showed that the level of blood lead was 0 2 90 μmol / L in 28 weeks of pregnancy and 0 32 6 μmol / L before delivery, and the level of blood lead increased during pregnancy. Blood lead levels in newborns were 0 333 μmol / L, of which 17 8% of neonates had higher blood lead levels than 0 483 μmol / L. Stepwise regression analysis showed that there was a highly linear relationship between blood lead level (Y3) and blood lead level (Y1) before delivery and blood lead level (Y2) within 28 weeks of pregnancy in neonates: Y3 = 0 12 2 5 10 6 7 + 0 16 0 945 91Y1 + 0 780 7786 5Y2. The linear correlation coefficient between Y3 and Y2 is r = 0 6 80 5, P <0 0 1. However, the level of maternal lead exposure has not had a significant effect on fetal growth and development