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目的:观察渴乐宁联合二甲双胍治疗2型糖尿病(T2DM)的临床疗效。方法:2005年6月—2007年6月期间,就诊的2型糖尿病病人200例,在相同的饮食控制及运动治疗的基础上,包括目前使用口服二甲双胍治疗的病人,随机分为治疗组100例,以渴乐宁联合二甲双胍治疗;对照组100例,以单纯口服二甲双胍治疗;疗程均为12周,观察两组空腹血糖(FPG)、餐后2h血糖(PPG2h)、糖化血红蛋白(HbA1C)治疗前后变化。结果:治疗组治疗后与对照组比较,FPG、PPG2h、HbA1C均下降(P<0.05),治疗组下降更明显(P<0.01),均有明确的统计学意义。结论:渴乐宁联合二甲双胍治疗2型糖尿病优于单纯口服二甲双胍,进而证明中西药联合治疗2型糖尿病疗效更佳。
Objective: To observe the clinical efficacy of thieleening combined with metformin in the treatment of type 2 diabetes mellitus (T2DM). Methods: Between June 2005 and June 2007, 200 patients with type 2 diabetes were enrolled in this study. Based on the same diet control and exercise therapy, including the current patients treated with oral metformin, they were randomly divided into treatment group (n = 100) Were treated with thielacine in combination with metformin. In the control group, 100 patients were treated with metformin alone. The course of treatment was 12 weeks. The levels of fasting blood glucose (FPG), postprandial blood glucose (PPG2h) and HbA1C Variety. Results: Compared with the control group, the levels of FPG, PPG2h and HbA1C in the treatment group decreased significantly (P <0.05), and the treatment group decreased more significantly (P <0.01). All of them had clear statistical significance. Conclusions: Thielapin plus metformin is superior to metformin alone in the treatment of type 2 diabetes mellitus, which proves that the combined treatment of traditional Chinese and western medicine is more effective in treating type 2 diabetes mellitus.