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目的:探讨血液稀释疗法联合羟基脲等药物治疗真性红细胞真多症的临床疗效及预后评价。方法:对我院收治的真性红细胞增多症患者采用治疗性血细胞单采术去除红细胞2~4次后,立即给予羟基脲等药物治疗。结果:经治疗性血细胞单采术去除红细胞后,患者外周血中红细胞计数明显下降,临床症状好转,再经羟基脲、阿司匹林等药物联合治疗,患者病情得到有效改善。结论:治疗性血细胞单采术联合药物治疗真性红细胞增多症有显著疗效。
Objective: To investigate the clinical efficacy and prognosis of hemodilution therapy combined with hydroxyurea and other drugs in the treatment of true polycythemia vera. Methods: The patients with polycythemia vera admitted to our hospital treated with hematopoietic cell apheresis to remove erythrocytes 2 to 4 times, immediately given hydroxyurea and other drugs. Results: After erythrocytes were removed by therapeutic blood cells apheresis, the number of erythrocytes in peripheral blood decreased significantly and the clinical symptoms improved. Combined treatment with drugs such as hydroxyurea and aspirin, the patients’ condition was effectively improved. Conclusion: Therapeutic hematocrit combined with drug treatment of polycythemia have a significant effect.