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目的探讨新生儿呼吸窘迫综合征(RDS)应用经鼻间歇正压通气疗法(NIPPV)的临床效果。方法将我院2011年8月-2013年8月RDS患儿120例分为两组各60例,观察组在予以肺表面活性物质(PS)后行经NIPPV;对照组在予以PS治疗后行经鼻持续气道正压通气疗法(NCPAP),比较两组治疗成功率及各项血气参数指标变化、术后并发症、住院费用情况。结果观察组治疗成功率显著高于对照组(P<0.05)、各项血气参数指标情况显著优于对照组(P<0.05)、术后并发情况及住院费用显著低于对照组(P<0.05)。结论 RDS应用NIPPV,可有效改善呼吸困难症状,促进康复,效果确切,术后并发少,医疗成本低,值得临床推广。
Objective To investigate the clinical effect of nasal intermittent positive pressure ventilation (NIPPV) in neonatal respiratory distress syndrome (RDS). Methods 120 patients with RDS in our hospital from August 2011 to August 2013 were divided into two groups of 60 patients. The observation group was treated with NIPPV after pulmonary surfactant (PS), while the control group was given nasal treatment after PS treatment Continuous positive airway pressure therapy (NCPAP) was used to compare the success rate of treatment and the changes of blood gas parameters, postoperative complications and hospitalization costs. Results The success rate of treatment in the observation group was significantly higher than that in the control group (P <0.05), and the indexes of blood gas parameters were significantly better than those in the control group (P <0.05). The postoperative complications and hospitalization costs were significantly lower than those in the control group ). Conclusion The application of NIPPV by RDS can effectively alleviate the symptoms of dyspnea and promote rehabilitation. It has definite effect, less postoperative complications and low medical costs, which deserves clinical promotion.