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我们曾发现,抗帕金森氏病新药By-701和樟柳碱对大鼠的学习和近记忆均有损害作用。主要表现为条件性回避反应(CAR)的平均反应时延长和出现率下降,实验动物对原来已熟悉的环境变得生疏,因而在测试中,受电击的次数增多,连续出现CAR的次数减少。在进行药物实验前,我们所选用的动物是经过三天预备性训练后,第3天CAR出现率达到80%者。这种CAR是新近形成的,是尚未得到巩固的,保持这种
We have found that anti-Parkinson’s disease, a new drug By-701 and anisodine on rat learning and near memory are damaging. Mainly as a result of the conditional response avoidance reaction (CAR) the average reaction time delay and the incidence of decline, experimental animals familiar to the environment has become unfamiliar, so in the test, the number of shocks increased, the number of consecutive CAR decreased. Before conducting the drug experiment, we selected animals after three days of preparatory training, CAR on the third day of 80%. This kind of CAR is a new formation that has not yet been consolidated, maintaining this