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中药川芎是活血化淤、行气定痛的药物。在临床观察和近代实验研究中已证明,其对急慢性缺血性血管疾病有肯定的疗效。川芎哚和川芎嗪一样也是有效生物碱,我们曾对川芎哚的药理作用进行过较为系统的研究,但用放射免疫方法研究其对血浆中CAMP(环-磷酸腺苷)含量的影响尚未见过报导。我们在研究川芎哚对小鼠冠脉血流量影响的基础上,本文用高灵敏度方法观察了其对血浆中CAMP水平的影响,以便探讨对生理功能和细胞代谢的作用。 CAMP是传递多种激素的“第二信使”的重要物质,而与CGMP是一对拮抗物质,普遍
Traditional Chinese medicine Chuanxiong is a drug that promotes blood circulation and stasis, and relieves pain. It has been proved in clinical observations and modern experimental studies that it has a positive effect on acute and chronic ischemic vascular diseases. Chuanxiong and Ligustrazine are also effective alkaloids. We have conducted systematic studies on the pharmacological effects of Ligusticum chuanxiong. However, it has not been seen that radioimmunoassay has an effect on plasma CAMP (cyclic adenosine monophosphate) content. Report. We have studied the effects of Chuanxiong on coronary blood flow in mice, and we investigated the effect of Chuanxiong on plasma CAMP levels with high sensitivity to explore the effects on physiological function and cell metabolism. CAMP is an important substance that transmits the “second messenger” of various hormones, and CGMP is a pair of antagonistic substances.