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目的了解大连西部地区急性脑梗死患者住院期间及出院180 d后二级预防药物和行为修正的依从性现状及依从性下降原因。方法调查2014年4月1日~2015年1月31日符合入组标准的急性脑梗死患者对于抗血小板药聚集药物、他汀药物、降压药物、降糖药物、抗凝药物治疗的使用率、戒烟行为修正率并随访180 d。结果入组患者中使用他汀等药物及抗凝药物依从性偏差,分别是50.1%和40.4%;不同药物二级预防依从性下降的原因不同;180 d后随访发现急性脑梗死发生率为6.4%。结论医生应关注患者有明确循证医学依据的二级预防药物及行为修正的依从性,并了解其下降的原因,采取针对措施提高患者药物治疗及行为修正的依从性。
Objective To understand the compliance status and the reasons for the decline in compliance of secondary preventive drugs and behavioral changes during hospitalization and 180 days after discharge in patients with acute cerebral infarction in the western part of Dalian. METHODS: Acute cerebral infarction patients who met the inclusion criteria from April 1, 2014 to January 31, 2015 were investigated for their use of antiplatelet agents, statin drugs, antihypertensive drugs, antidiabetic drugs, and anticoagulant drugs, Cigarette smoking correction rate and follow-up 180 d. Results The compliance rates of statins and other drugs used in the patients were 50.1% and 40.4%, respectively. The reasons for the different prevention of secondary prevention of different drugs were different. The incidence of acute cerebral infarction was found to be 6.4% . Conclusions Doctors should pay attention to patients’ compliance with secondary evidence of preventive medicine and behavioral modification based on evidence-based medicine, understand the reasons for their decline, and take measures to improve compliance with medication and behavioral modification.