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[目的]观察赛胃安胶囊对反流性食管炎的疗效。[方法]80例反流性食管炎患者按入组先后分为治疗组、对照组,每组40例。对照组予以耐信+莫沙必利治疗,治疗组在对照组治疗的基础上加服赛胃安胶囊。比较2组患者治疗1周、8周后临床症状变化,同时比较治疗8周后内镜下食管炎改善情况。[结果]治疗1周后,治疗组临床症状改善为显效31例、有效8例、无效1例,总有效率为97.5%;对照组显效23例、有效12例、无效5例,总有效率87.5%;治疗组疗效优于对照组,差异有统计学意义(P<0.05)。治疗8周后,治疗组显效37例、有效3例、无效0例,总有效率100%;对照组显效34例、有效4例、无效2例,总有效率95.0%;治疗组疗效优于对照组,但差异无统计学意义(P>0.05)。治疗8周后反流性食管炎恢复情况,治疗组显效33例、有效5例、无效2例,总有效率95.0%;对照组显效24例、有效12例、无效4例,总有效率90.0%;治疗组明显优于对照组(P<0.05)。[结论]赛胃安胶囊能促进反流性食管炎的愈合,并有助于改善反流性食管炎的临床症状。
[Objective] To observe the effect of saiweian capsule on reflux esophagitis. [Method] 80 patients with reflux esophagitis were divided into treatment group and control group according to the intervention group, 40 cases in each group. The control group was treated with metoxin + mosapride and the treatment group was treated with saiwei capsule on the basis of the control group. The clinical symptoms of the two groups were compared after one week and eight weeks of treatment, and the endoscopic esophagitis was compared after 8 weeks of treatment. [Results] After 1 week of treatment, the clinical symptoms of the treatment group were improved markedly in 31 cases, effective in 8 cases and ineffective in 1 case, the total effective rate was 97.5%; in the control group, 23 cases were markedly effective, 12 cases were effective and 5 cases were ineffective. The total effective rate 87.5%. The curative effect in the treatment group was better than that in the control group, the difference was statistically significant (P <0.05). After 8 weeks of treatment, the treatment group was markedly effective in 37 cases, effective in 3 cases, ineffective in 0 cases, the total effective rate was 100%; the control group markedly effective in 34 cases, effective in 4 cases, ineffective in 2 cases, the total effective rate was 95.0% Control group, but the difference was not statistically significant (P> 0.05). The recovery of reflux esophagitis 8 weeks after treatment, the treatment group markedly effective in 33 cases, effective in 5 cases, invalid in 2 cases, the total effective rate was 95.0%; control group of 24 cases markedly effective in 12 cases, 4 cases, the total effective rate 90.0 %; Treatment group was significantly better than the control group (P <0.05). [Conclusion] SAVE Capsule can promote the healing of reflux esophagitis and help to improve the clinical symptoms of reflux esophagitis.