论文部分内容阅读
目的探讨保妇康栓对妇科恶性肿瘤术后并发老年性阴道炎临床疗效、生活质量和安全性的影响。方法将妇科恶性肿瘤术后并发老年性阴道炎患者80例随机分为观察组和对照组各40例,对照组患者给予戊酸雌二醇片治疗,观察组患者给予保妇康栓治疗,两组患者均以2周为观察疗程。结果观察组患者治疗总有效率为95.00%显著优于对照组患者72.50%,差异有统计学意义(P<0.05)。两组患者阴部瘙痒和阴部干涩灼痛评分治疗后较治疗前下降,且差异有统计学意义(P<0.05);治疗后观察组患者阴部瘙痒和阴部干涩灼痛评分低于对照组患者,差异有统计学意义(P<0.05)。治疗后3个月两组患者生活质量评分较治疗前升高,差异有统计学意义(P<0.05);且观察组高于对照组,差异有统计学意义(P<0.05)。观察组患者不良反应发生率5.00%低于对照组患者27.50%,差异有统计学意义(P<0.05);观察组患者治疗后3个月复发率2.50%低于对照组患者20.00%,差异有统计学意义(P<0.05)。结论保妇康栓对妇科恶性肿瘤术后并发老年性阴道炎临床疗效显著,可减轻患者症状,提高患者生活质量,且不良反应少、复发率低,安全性良好。
Objective To investigate the effect of Baofukang suppository on the clinical efficacy, quality of life and safety of patients with senile vaginitis after gynecological malignant tumor. Methods Eighty patients with senile vaginitis after gynecologic malignancy were randomly divided into observation group and control group, 40 cases in each group. The control group was treated with estradiol valerate, while the observation group was treated with Baofukang suppository. Patients in the two groups were observed for 2 weeks. Results The total effective rate of observation group was 95.00%, which was significantly better than that of control group (72.50%), the difference was statistically significant (P <0.05). The scores of pruritus genitals and genitals burns score in both groups were significantly lower than those before treatment (P <0.05). After treatment, the scores of pruritus and genital dryness in the observation group were lower than those in the control group There was statistical significance (P <0.05). After 3 months of treatment, the quality of life scores of the two groups were significantly higher than those before treatment (P <0.05), and the observation group was higher than the control group (P <0.05). The incidence of adverse reactions in the observation group was 5.00% lower than that in the control group (27.50%), the difference was statistically significant (P <0.05); the recurrence rate in the observation group was 2.50% at 3 months after treatment was lower than that in the control group 20.00% Statistical significance (P <0.05). Conclusion Baofukang suppository has significant clinical effect on postoperative complications of senile vaginitis in gynecologic malignancies. It can alleviate the symptoms of patients and improve the quality of life of patients with less adverse reactions, low recurrence rate and good safety.