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目的 评估双钢板结合自体骨移植技术治疗股骨干骨折术后无菌性骨不连的疗效.方法 2009年1月-2013年1月解放军总医院收治的应用双钢板联合自体骨移植治疗的21例股骨干骨折术后无菌性骨不连患者,男15例,女6例;年龄25~81(46.9±14.56)岁.骨不连根据Weber-Cech分型:萎缩型14例,肥大型7例,全部患者均获得6个月以上的随访.术后通过健康状况调查问卷SF-36对患者进行评估.结果 X线复查显示所有骨不连患者术后均获得愈合,术后无相关并发症发生.SF-36生理功能评分为90~99,平均96;SF-36躯体疼痛评分为92~99,平均94.2.结论 双钢板结合自体骨移植技术具有高愈合率和低并发症率的特点,有利于骨不连的愈合,可以作为股骨干骨折术后无菌性骨不连的有效治疗方法 .“,”Objective To assess the effectiveness of double locking plate fixation with autogenous bone graft for the treatment offemoral shaft aseptic nonunion. Methods Twenty-one patients(15 males and 6 females with the average age of 46.9 years, rangingfrom 25-81 years) with aseptic nonunion of femoral shaft fracture were treated with double locking plate with autogenous bonegraft between January 2009 and January 2013, and their clinical data were retrospectively analyzed. According to the Weber-Cechclassification, 14 cases were rated as atrophic nonunion, and 7 cases as hypertrophic nonunion. All patients were followed up over6 months and assessed postoperatively by short form-36 health survey (SF-36). Results Osseous union was observed clinically andradiographically in all patients, and no related complications were noted postoperatively. Average scores of the physical functionand bodily pain dimensions of the SF-36 were 96 (range, 90–99) and 94.2 (range, 92–99), respectively. Conclusion Due to the highunion rates and low complication rates in our study, double locking plate fixation with autogenous bone graft can serve as an effectivemethod of femoral shaft nonunion.