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目的观察分析孟鲁司特钠片与布地奈德联合应用治疗老年支气管哮喘的临床疗效。方法选择医院呼吸科2013年1月-2015年2月收治的老年支气管哮喘患者90例,随机分为观察组和对照组各45例。对照组在常规内科方法的基础上加用布地奈德雾化吸入进行治疗,观察组在对照组的基础上加用孟鲁司特钠咀嚼片进行治疗,比较2组的临床疗效、咳嗽缓解时间、喘息缓解时间、胸闷缓解时间以及白天和夜间哮喘的发作次数。结果观察组总有效率为91.1%明显高于对照组的75.6%,差异有统计学意义(P<0.05);观察组咳嗽缓解时间、胸闷缓解时间、喘息缓解时间以及白天和夜间哮喘发作次数均明显低于对照组,差异有统计学意义(P<0.05)。结论采用孟鲁司特钠片与布地奈德联合应用治疗老年支气管哮喘,可以明显的减轻患者的临床症状以及哮喘发作次数,提高疗效。
Objective To observe the clinical efficacy of montelukast sodium tablets combined with budesonide in the treatment of elderly bronchial asthma. Methods Ninety elderly patients with bronchial asthma admitted from January 2013 to February 2015 in our hospital were randomly divided into observation group (45 cases) and control group (45 cases). The control group was treated with inhalation of budesonide inhalation on the basis of conventional medical methods. The observation group was treated with montelukast sodium chewable tablets on the basis of the control group. The clinical curative effect, cough remission time , Wheezing relief time, chest tightness relief time, and the number of asthma attacks during the day and night. Results The total effective rate in the observation group was 91.1%, which was significantly higher than that in the control group (75.6%, P <0.05). The cough relief time, chest tightness relief time, wheezing relief time and the number of asthma attacks during the day and night in the observation group Significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusion The combination of montelukast sodium and budesonide in the treatment of elderly bronchial asthma can significantly reduce the patient’s clinical symptoms and the number of asthma attacks and improve the efficacy.