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目的观察奥美拉唑联合阿莫西林、甲硝唑治疗消化性溃疡的临床效果。方法选取医院收治的消化性溃疡患者90例为研究对象,随机分为2组,每组各45例。对照组采用雷尼替丁联合阿莫西林、甲硝唑进行治疗,观察组采用奥美拉唑联合阿莫西林、甲硝唑进行治疗,观察2组临床治疗效果及不良反应发生情况。结果观察组治疗总有效率为95.56%,高于对照组的77.78%,2组比较差异具有统计学意义(P<0.05);观察组不良反应发生率为6.67%,低于对照组的22.22%,2组比较差异具有统计学意义(P<0.05)。结论奥美拉唑联合阿莫西林、甲硝唑治疗消化性溃疡,临床效果显著,不良反应少,安全可靠,具有临床推广应用价值。
Objective To observe the clinical effects of omeprazole combined with amoxicillin and metronidazole in the treatment of peptic ulcer. Methods Totally 90 patients with peptic ulcer admitted to hospital were selected as study subjects and randomly divided into 2 groups with 45 cases in each group. The control group was treated with ranitidine combined with amoxicillin and metronidazole. The observation group was treated with omeprazole combined with amoxicillin and metronidazole. The clinical effects and adverse reactions of the two groups were observed. Results The total effective rate of the observation group was 95.56%, which was higher than that of the control group (77.78%). The difference between the two groups was statistically significant (P <0.05). The incidence of adverse reactions in the observation group was 6.67%, lower than that of the control group (22.22% , The difference between the two groups was statistically significant (P <0.05). Conclusion Omeprazole combined with amoxicillin and metronidazole in the treatment of peptic ulcer has significant clinical effect, less adverse reactions, safe and reliable, and has clinical application value.