托吡酯(Topiramate)是一种新型抗癫痫药,具有多重抗癫痫作用。其优点是口服吸收好,生物利用度高,与其他药物相互作用少。然而,随着该药的临床广泛应用,其不良反应也渐为广大医师所认识。2003年6月至2006年1月,我们应用托吡酯对51例门诊癫痫患者进行了治疗,现就其不良反应发生情 Topiramate is a new antiepileptic drug with multiple antiepileptic effects. Its advantages are good oral absorption, high bioavailability, and less interaction with other drugs. However, with the widespread use of the drug in clinical practice, its adverse reactions are gradually recognized by the majority of physicians. From June 2003 to January 2006, we applied topiramate to 51 outpatients with epilepsy and were treated for adverse reactions