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伪膜性肠炎是由难辨梭状芽胞杆菌引起的肠道急性炎症性疾病,我们用去甲基万古霉素和丽珠肠乐治疗50例.获很好疗效.现报告如卜: 1 资料与方法 1.1 病例选择 诊断际准:应用抗生索后出现腹泻;大便培养分离出难辨陵状芽胞杆菌;纤维结肠镜检查发现典型伪膜。符合标准者共75例,治疗组50例,其中男28例,女22例,年龄36岁～78岁(平均52岁);对照组25例,其中男12例,女13例,年龄31岁～76岁(平均48岁)。 1.2 治疗方法 两组均停用相关抗生累.静脉输液维持水电解质平衡.治疗组用去甲基万古霉素0.25g.po,qid,疗程7d.继而用丽珠肠乐1g(1亿活菌数/g),po,bid,疗程7d。对照组仅用去甲基万古霉素治疗,方法同上。
Pseudomembranous colitis is an acute inflammatory disease of the intestinal tract caused by Clostridium difficile. We treated 50 patients with demethylation of vancomycin and lamellae and achieved good results. And Methods 1.1 Case Selection Diagnostic criteria: diarrhea after application of antibacterial rope; isolated from stool culture of Bacillus pumilus; colonoscopy found typical pseudomembranous. A total of 75 cases met the standard, the treatment group of 50 patients, including 28 males and 22 females, aged 36 to 78 years (mean 52 years); control group of 25 patients, including 12 males and 13 females, aged 31 years ~ 76 years old (average 48 years old). 1.2 The two groups were disabled anti-antibiotic tired intravenous infusion to maintain water and electrolyte balance .Treatment group with demethylation of vancomycin 0.25g.po, qid, treatment 7d. And then with Lizhu Changle 1g (100 million live bacteria Number / g), po, bid, treatment 7d. The control group was treated with desmethyl vancomycin only, as above.