The Spanish medic Alonso de Santa Cruz,wrote the short treaty called Opusculum de Melancholia,circa 1569,which was not published until 1662 along with other works from his son Antonio Ponce de Santa Cruz,chamber medic for the kings Phillip III and Phillip IV.That work,heir of the tradition of the galenic medicine,molded by the comments of Arab philosophers and doctors,unfolds a wide range perspective of the European Renaissance vision about melancholy as a disease.Melancholy itself is constructed by the symbolic structure of a myth(Bartra) and as such enunciates elements and mechanisms which produce representations that put existence into condition.Inside myth’s meanders arises another idea:lycanthropy.Its very own origin escapes us,but it remains related to magic and ancient shamanism(Wagner).Melancholy assumes inside the ground of its representations the insania lupina(lycanthropy).The way to generate a representation model is to start from effective analogy,stimulated by a rhetoricity which operates in the discourse,and also fulfill the mission of persuade through cases exposition(docere).Even though the treaty About Melancholy has a rigorously scientistic intention(telos),rational in this sense,in the comprehension of the body as a place that exhibits a determined casualty,there is an aesthetic principle that conditions the spectrum of melancholy,even within medic treaties,above all within them.Medic texts as literary-scientific documents provide us with a series of signs which are linked to a knowledge that doesn’t understands body as an entity separated from nature,that is from the cosmos,generates an idea of melancholy which always signals the crepuscular limit between the eye that observes and the object that is observed.Melancholy becomes more than just an empirical description therefore experimental,from a determined human nature(perhaps the first to signal the lack of an empiric evidence bounded knowledge in galenic medicine was Paracelso,who imagined and perhaps saw his books burned in and endless bonfire),in a place for phantasmagoric and symbols production,in a sphere for those transgressors of the divine or civil order,or for those whose transgression is founded in the search for freedom,towards a last instance understanding of the sphere containing another great idea:madness(Foucault). The Spanish medic Alonso de Santa Cruz, wrote the short treaty called Opusculum de Melancholia, circa 1569, which was not published until 1662 along with other works from his son Antonio Ponce de Santa Cruz, chamber medic for the kings Phillip III and Phillip IV. That work, heir of the tradition of the galenic medicine, molded by the comments of Arab philosophers and doctors, unfolds a wide range perspective of the European Renaissance vision about melancholy as a disease. Melancholy itself is constructed by the symbolic structure of a myth ( Bartra) and as such such agency products and mechanisms which produce representations that put existence into condition. Inside myth’s meanders arises another idea: lycanthropy.Its very own origin escapes us, but it remains related to magic and ancient shamanism (Wagner) .Melancholyurrent inside the ground of its representations the insania lupina (lycanthropy). The way to generate a representation model is to start from effective analogy, stimulated by a rhetorici ty which serves in the discourse, and also fulfill the mission of persuade through cases exposition (docere) .Even though the treaty About Melancholy has a rigoristically scientistic intention (telos), rational in this sense, in the comprehension of the body as a place that exhibits a determined casualty, there is an aesthetic principle that conditions the spectrum of melancholy, even within medic treaties, above all within them. ’t understands body as an entity separated from nature, that is from the cosmos, generates an idea of ​​melancholy which always signals the crepuscular limit between the eye that observes and the object that is observed. Melancholy becomes more than just an empirical description of experimental , from a determined human nature (perhaps the first to signal the lack of an empiric evidence bounded knowledge in galenic medicine was Paracelso, who imagined andperhaps saw his books burned in and endless bonfire), in a place for phantasmagoric and symbols production, in a sphere for those transgressors of the divine or civil order, or for those whose transgression is founded in the search for freedom, towards a last instance understanding of the sphere containing another great idea: madness (Foucault).