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药理作用有两种:(一)PAB能抑制立克次体在人体细胞内的增殖,使身体产生的免疫体,可以乘机制服它。倘治疗停止过早,则残留体内的立克次体仍有机会增殖,使病复发。(二)PAB有解除斑疹伤寒毒素之作用,常见之毒性现象如肾脏机能障得,便可免发生。PAB由肠道吸收甚快,由肾排泄亦甚快。血液中之有效浓度为60-80毫克/100毫升,倘超过80毫克/100毫升,则可发生中毒现象。
Pharmacological effects in two ways: (a) PAB can inhibit the proliferation of rickettsia in human cells, the body of the immune body, you can take the opportunity to subdue it. If the treatment is stopped too early, the residual body of rickettsia still have the opportunity to proliferate, the disease recurrence. (B) PAB have typhus toxins to relieve the role of common toxic phenomena such as kidney dysfunction, can be avoided. PAB absorbed rapidly from the intestine, excreted by the kidneys also very fast. The effective concentration of blood in the 60-80 mg / 100 ml, if more than 80 mg / 100 ml, then poisoning can occur.