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与人Ⅰ型T淋巴细胞病毒(HTLV-1)相关的脊髓病变(HAM)是一种被认为与HTLV-1感染有关的慢性进行性脊髓麻痹。本病1986年自由纳等报告以来,作为一种可治性的脊髓麻痹疾病已为世界所关注,认为与1985年Gessain等报告的HTLV-1抗体阳性的热带痉挛性双侧麻痹(TSP)为同一疾病,现在主张称之为HAM-TSP。起初认为本病是脊髓病变,而最近已经明确尚存在肺、眼、皮肤等中枢神经以外的脏器病变,故有必要将本病作为一种伴随HTLV-1感染的全身性疾病来认识。本文就HAM并发的肺病变予以概述,同时还就未发生HAM的HTLV-1携带者存在肺病变的可能性进行探讨。
Spinal cord disease (HAM) associated with human type I T lymphocyte virus (HTLV-I) is a chronic progressive spinal paralysis associated with HTLV-1 infection. This disease has been reported since Liberty et al. In 1986. As a treatable disease of spinal paralysis, it is of concern to the world that, in 1985, the HTLV-1 antibody-positive tropical spastic bipolar paralysis (TSP) reported by Gessain et al. The same disease, now advocated as HAM-TSP. Initially considered the disease is myelopathy, and recently there is clear existence of lung, eye, skin and other organ diseases other than the central nervous system, it is necessary to the disease as a systemic disease associated with HTLV-1 infection to recognize. This article presents an overview of concurrent lung lesions in HAM and also explores the possibility of lung lesions in HTLV-1 carriers who do not develop HAM.