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观察368例高血压病患者美托洛尔治疗10周前后的血压、左室重量指数（LVMI）、左至壁平均厚度（MWTd）及心功能指标：左室对血分数（LVEF）、每博输出量（SV）、二尖瓣E／A峰速度比的变化。治疗后SBP、LVMI、PWTd比治疗前明显减少（P＜0．001）。SBP与LVMI呈正相关（r＝0．386）。心功能指标改善。提示美托洛尔降压的同时可使高血压性左心室肥厚逆转。
The blood pressure, left ventricular mass index (LVMI), mean left wall thickness (MWTd) and cardiac function were measured in 368 hypertensive patients before and after metoprolol treatment: LVEF, Output (SV), mitral E / A peak velocity ratio changes. The SBP, LVMI and PWTd decreased significantly after treatment (P <0.001). SBP was positively correlated with LVMI (r = 0.386). Cardiac function improved. Tip Metoprolol at the same time can make hypertensive left ventricular hypertrophy reversed.