常染色体显性遗传性多囊肾病(autosomal dominant polycystic kidney disease,ADPKD)的早期常出现高血压且与ADPKD患者进展至终末期肾病(endstage renal disease,ESRD)及死于心血管疾病相关。临床研究表明肾素血管紧张素醛固酮系统(rennin angiotensin aldsterone system,RAAS)在ADPKD患者高血压发生过程中发挥关键作用。但采用更积极的降 Autosomal dominant polycystic kidney disease (ADPKD) often presents with hypertension early and is associated with progression to end-stage renal disease (ESRD) and cardiovascular death in patients with ADPKD. Clinical studies have shown that renin angiotensin aldosterone system (RAAS) plays a key role in the development of hypertension in ADPKD patients. But adopt a more positive drop