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目的：探讨抗滋养细胞膜抗原（ Ｔ Ａ） Ｉｇ Ｇ 类抗体与原因不明性流产的关系。方法：采用酶联免疫吸附实验（ Ｅ Ｌ Ｉ Ｓ Ａ）检测９５例流产妇女及５２例正常妊娠妇女血清中抗滋养细胞膜抗原（ Ｔｒｏｐｈｏｂｌａｓｔ ａｎｔｉｇｅｎ， Ｔ Ａ） Ｉｇ Ｇ 类抗体的水平。结果：流产妇女血清中抗滋养细胞膜抗原 Ｉｇ Ｇ 类抗体水平明显高于正常妊娠妇女（ Ｐ＜ ０００１）；流产妇女血清抗滋养细胞膜抗原 Ｉｇ Ｇ 类抗体水平与孕次呈正相关（ｒ＝ ０．９１， Ｐ＜ ００５）。结论：血清中抗滋养细胞膜抗原 Ｉｇ Ｇ 类抗体水平可以作为流产免疫因素的一个特异性的辅助诊断指标。
Objective: To investigate the relationship between anti-trophoblast antigen (T A) Ig G antibody and unexplained abortion. Methods: Serum levels of anti-trophoblast antigen (T-A) Ig G antibodies in 95 abortion women and 52 normal pregnant women were detected by enzyme-linked immunosorbent assay (ELISA). Results: The level of anti-trophoblast antigen Ig G antibody in the serum of abortion women was significantly higher than that of the normal pregnant women (P <0001). The level of Ig G antibody of serum anti-trophoblast antigen was positively correlated with the pregnancy time (r = 0 .91, P <005). Conclusion: The level of anti-trophoblast antigen Ig G antibody in serum can be used as a specific auxiliary diagnostic indicator of immune factors of abortion.