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本文应用电镜观察了一次静脉注射参芪液60ml 前后对冠心病心气虚患者血小板聚集的影响。结果提示用药前冠心病心气虚患者与正常相比血小板扩聚型和聚集数都明显增加,用药后一小时上述异常现象明显好转。用家兔血小板体外实验表明参芪液对ADP 诱导的血小板聚集也有抑制作用。血小板超微结构的初步观察提示对血小板的伪足形成及颗粒释放也可能有一定抑制作用。
In this paper, electron microscopy was used to observe the effect of intravenous injection of Shenqi liquid 60ml on the platelet aggregation of patients with CHD. The results suggest that the concentration of thrombocytopenia and aggregation of thrombocytopenia in patients with coronary heart disease with heart qi deficiency are significantly increased before treatment, and the above abnormalities are significantly improved within one hour after administration. In vitro experiments with rabbit platelets showed that Shenqi liquid also inhibited ADP-induced platelet aggregation. Preliminary observations of platelet ultrastructure suggest that platelet pseudopodia formation and granule release may also be inhibited.