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目的探讨和分析ADR的发生因素、特点以及常见的并发症,为药物的安全性分析和合理用药提供科学依据。方法对我院2002年1月～2010年5月收入院的100例ADR患者进行回顾性统计和分析。结果 ADR的发生率在20～60岁、使用抗感染药的患者中最高,ADR表现为皮肤损害、胃肠道反应、精神症状、神经症状、锥体外系反应等。结论加强对ADR监测、探讨和分析,使ADR的发生减少,从而保证临床用药的安全性。
Objective To investigate and analyze the occurrence factors, characteristics and common complications of ADR, and provide scientific basis for drug safety analysis and rational drug use. Methods A retrospective statistical analysis of 100 ADR patients admitted to our hospital from January 2002 to May 2010 was conducted. Results The incidence of ADR ranged from 20 to 60 years. The highest ADR was in patients with anti-infectives. The ADR showed skin lesions, gastrointestinal reactions, psychiatric symptoms, neurological symptoms and extrapyramidal reactions. Conclusion To strengthen the monitoring, discussion and analysis of ADR to reduce the incidence of ADR, so as to ensure the safety of clinical medication.