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目的探讨阿司匹林联合双嘧达莫在预防急性缺血性脑卒中后发生脑血管缺血事件的应用价值。方法将我院收治的急性缺血性脑卒中患者82例随机分为两组各41例,对照组给予阿司匹林治疗,观察组在对照组基础上给予患者缓释型双嘧达莫治疗,观察两组疗效。结果观察组神经功能缺损评分改善情况优于对照组,差异有统计学意义(P<0.05)。随访6个月后观察组卒中复发率及一过性脑缺血发作率均低于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率无统计学差异(P>0.05)。结论阿司匹林联合缓释型双嘧达莫可有效改善急性缺血性脑卒中患者神经功能,降低脑血管缺血事件的再发生率,不良反应轻微,值得临床推广。
Objective To investigate the value of aspirin combined with dipyridamole in the prevention of cerebrovascular ischemia after acute ischemic stroke. Methods 82 cases of acute ischemic stroke admitted to our hospital were randomly divided into two groups of 41 cases. The control group was given aspirin. The observation group was treated with sustained-release dipyridamole on the basis of the control group. Group efficacy. Results The improvement of neurological deficit score in observation group was better than that in control group (P <0.05). After 6 months of follow-up, the recurrent rate of stroke and the rate of transient ischemic attack in the observation group were lower than those in the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusions Aspirin combined with extended-release dipyridamole can effectively improve the neurological function and reduce the recurrence rate of cerebrovascular ischemic events in patients with acute ischemic stroke. The adverse reaction is mild and worthy of clinical promotion.