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目的:通过对单脐动脉胎儿的畸形类型及妊娠结局的追踪,分析单脐动脉对妊娠的影响及临床意义。方法:回顾分析2008年以来在郑州大学第三附属医院住院分娩的54例单脐动脉孕妇的畸形类型、诊断方法、分娩方式及妊娠结局。结果:54例病例中,无胎儿发育异常的19例,单脐动脉合并胎儿宫内生长受限15例,单脐动脉合并胎儿发育异常14例。单脐动脉合并羊水过多5例,合并羊水过少6例,羊水Ⅱ°以上污染13例;宫内死胎4例,早产13例,足月产37例。结论:单脐动脉合并畸形中,以心脏发育异常最常见;单纯性单脐动脉胎儿产前诊断排除染色体异常,同时加强孕期及产程监护,及早发现胎儿宫内生长受限及胎儿宫内窘迫,提高新生儿出生质量。
OBJECTIVE: To analyze the effect of single umbilical artery on pregnancy and its clinical significance by tracking the deformity and pregnancy outcome of single umbilical artery fetus. Methods: The types of malformations, diagnosis methods, modes of delivery and pregnancy outcomes of 54 single umbilical artery pregnant women who were hospitalized and delivered in the Third Affiliated Hospital of Zhengzhou University from 2008 onwards were retrospectively analyzed. Results: Among the 54 cases, there were 19 cases without abnormal fetal development, 15 cases with unilateral umbilical artery with limited fetal growth, and 14 cases with unilateral umbilical artery with abnormal fetal development. Single umbilical artery with amniotic fluid in excess in 5 cases, with oligohydramnios in 6 cases, amniotic fluid Ⅱ ° more than 13 cases of pollution; intrauterine fetal death in 4 cases, 13 cases of preterm birth, 37 cases of full-term. Conclusions: Cardiac dysplasia is most common in unilateral umbilical artery malformations. Prenatal diagnosis of simple umbilical artery fetuses precludes chromosomal abnormalities. At the same time, it strengthens the monitoring of pregnancy and labor, early detection of fetal growth restriction and fetal distress, Improve newborn birth quality.