论文部分内容阅读
评价原发性肝癌患者免疫栓塞治疗前后的免疫指标变化。经肝动脉灌注沙培林碘化油乳剂治疗肝癌患者 16例 ,治疗前后用流式细胞仪检测外周血淋巴细胞亚群的比例 ,并与单纯栓塞组 (19例 )比较。结果 ,治疗前患者的CD3+ 、CD4+ 细胞比例、CD4+ /CD8+ 比值低于正常 ,而CD8+ 细胞比例则高于正常。治疗后CD3+ 、CD4+ 、NK细胞比例、CD4+ /CD8+ 比值均较治疗前升高 ,并且较单纯栓塞组更为显著。在原发性肝癌患者的细胞免疫状态低下 ,免疫栓塞治疗可显著改善肝癌患者的细胞免疫状态。
To evaluate the changes of immune parameters before and after immunoembolization in patients with primary liver cancer. Hepatocellular infusion of Shapalin iodized oil emulsion was used to treat 16 patients with hepatocellular carcinoma. The percentage of lymphocyte subsets in peripheral blood was measured by flow cytometry before and after treatment, and compared with the simple embolization group (19 cases). As a result, the ratio of CD3+, CD4+ cells, and CD4+/CD8+ ratio were lower than normal before treatment, and the proportion of CD8+ cells was higher than normal. After treatment, the proportions of CD3+, CD4+, NK cells, and CD4+/CD8+ ratio were all higher than those before treatment, and were more significant than those in the simple embolization group. In patients with primary liver cancer, the cellular immune status is low, and immune embolization can significantly improve the cellular immunity of patients with liver cancer.